With the popularity of mobile smart devices, Mobile Crowd Sensing (MCS) has been widely used while facing serious privacy leaks. Focusing on the issue that the existing original data privacy protection scheme is unable to resist collusion attacks and reduce the perception data availability, a Data Privacy Protection algorithm based on Mobile Node (DPPMN) was proposed. Firstly, the node manager in DPPMN was used to establish an online node list and send it to the source node. An anonymous path for data transmission was built by the source node through the list. Then, the data was encrypted by using paillier encryption scheme, and the ciphertext was uploaded to the application server along the path. Finally, the required perception data was obtained by the server using ciphertext decryption. The data was encrypted and decrypted during transmission, making sure that the attacker was not able to wiretap the content of the perception data and trace the source of the data along the path. The DPPMN ensures that the application server can access the original data without the privacy invasion of the nodes. Theoretical analysis and experimental results show that DPPMN has higher data security with increasing appropriate communication, and can resist collusion attacks without affecting the availability of data.